Introduction to Genomics, Proteomics, and Bioinformatics (IGPB)

UMDNJ-Graduate School of Biomedical Sciences


Course director: Dr.Bin Tian

Course number: BIOC N5002 (3 credits)

Course prerequisite: Basic biochemistry and molecular biology

Topics:

Genomics:

  • Genome projects
  • Genome sequencing
  • Genome structure and function
  • Comparative genomics
  • Human genome variation, including SNPs and Haplotype
  • Human Disease Gene Mapping
  • Pharmacogenomics and Individualized Medicine

Transcriptomics:

  • cDNA/EST
  • SAGE and other tag-based technologies
  • DNA microarrays
  • Next-generation sequencing

Proteomics:

  • Protein Structure and Function
  • Analytical Technologies for Proteomics
  • Mass Spectrometry
  • Emerging Technologies in Proteomics

Bioinformatics:

  • Sequence alignment and database search
  • Phylogenetic anlaysis of sequences
  • Digital gene expression analysis using sequence tags
  • DNA microarray analysis
  • Analysis of proteomics data
  • Hidden Markov Models for sequence analysis
  • RNA structure prediction
  • Gene network
  • Gene ontology

Course details:

Spring, 2005

Fall, 2005

Fall, 2006

Fall, 2007

Fall, 2008

Fall, 2009