Introduction to Genomics, Proteomics, and Bioinformatics (Fall, 2006)


Time: Tuesday, 6:00 - 7:30 PM

Place: MSB-E609b, UMDNJ-New Jersey Medical School

Course coordinator: Dr. Bin Tian  

Syllabus:

Date

Instructor

Topic (Click to download lecture slides)

Section I: Genomes

1

8/29/06

Dr. Tian

Course overview/Genome structure

2

9/5/06 

Dr. Donnelly

DNA sequencing and genome projects

3

9/12/06

Dr. Tian

Comparative Genomics

4 9/19/06  Dr. Diehl Using SNPs for disease gene discovery and pharmacogenomics

Exam I

Section II: Transcriptome

5

9/26/06 

Dr. Tian

Gene expression and cDNA/EST/SAGE

6

10/3/06 

Dr. Tian

Sequence comparison algorithms

7

10/10/06 

Dr. Soteropoulos 

DNA microarray I: platforms

8

10/17/06

Dr. Aris 

DNA microarray II: analysis

Exam II

Section III: Proteome

9

10/24/06 

Dr. Li

Overview of protein structure and funtion

10

10/31/06 

Dr. Tian

Hidden Markov Models: Prediction of protein domains and genes

11

11/7/06

Dr. Li

Analytical technologies for proteomics

12

11/14/06

Dr. Li

Mass spectrometry: technique and analysis

Exam III

Section IV: Special topics

13 11/21/06 Dr. Diehl Advanced technologies for DNA sequencing and polymorphism detection
14 11/28/06 Dr. Yan Mass spectrometry applications
15 12/5/06 Dr. Oh Bayesian Statistics: Basics and Applications

16

12/12/06

Dr. Tian

Gene ontology and gene pathway

Exam IV

Grading:

Attendance/participation: 10%; 

Exams: 90% (4 take-home exams comprising 16 questions/small projects). 

Instructors:  

Dr. Virginie M. Aris(arisvm@umdnj.edu), Center for Applied Genomics, PHRI.

Dr. Scott Diehl (diehlsr@umdnj.edu), Center for Pharmacogenomics and Complex Disease Research, NJDS.

Dr. Bob Donnelly (donnelly@umdnj.edu), Molecular Resource Facility, NJMS.

Dr. Hong Li (liho2@umdnj.edu), Center for Advanced Proteomics Research, NJMS.

Dr. Cheongeun Oh (ohch@umdnj.edu), Department of Preventive Medicine & Community Health, NJMS.

Dr. Patricia Soteropoulos (soteropoulos@phri.org), Center for Applied Genomics, PHRI.

Dr. Bin Tian (btian@umdnj.edu), Department of Biochemistry and Molecular Biology, NJMS.

Dr. Lin Yan  (yanl2@umdnj.edu), Department of Cell Biology & Molecular Medicine, NJMS.