Bin Tian, Ph.D. Associate Professor Department of Biochemistry and Molecular Biology UMDNJ-New Jersey Medical School 185 South Orange Avenue, MSB-E501 Newark, NJ 07101-1709 Tel: (973) 972-3615 Fax: (973) 972-5594 Email: btian [at] umdnj.edu

Our lab studies RNA biology using computational and molecular biology approaches. We are particularly interested in post-transcriptional gene regulation in development and disease. Currently, we are investigating the evolution of alternative cleavage and polyadenylation (APA) in metazoans; mechanisms and consequences of APA in cell proliferation and differentiation; transcriptomics in cardiac remodeling; and long non-coding RNAs in cell differentiation.

Keywords of Recent Projects: mRNA polyadenylation | alternative polyadenylation | alternative splicing | post-transcriptional gene regulation | 3'UTR | RNA structure | microRNA | transposable elements | brain | testis | heart | embryonic development | induced pluripotent stem cells | cardiac hypertrophy | ischemia/reperfusion | aging | CstF-77