Welcome to PolyA_DB, a web resource for pre-mRNA cleavage and polyadenylation sites (polyA sites)

 


PolyA site databases

PolyA_DB 1

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PolyA_DB version 1 contains human and mouse polyA sites mapped by cDNA/EST sequences.

Reference: Zhang, H., Hu, J., Recce, M., and Tian, B. (2005). PolyA_DB: a database for mammalian mRNA polyadenylation. Nucleic Acids Res. 33:D116-20.
PolyA_DB 2

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PolyA_DB version 2 contains polyA sites in human, mouse, rat, chicken and zebrafish that are mapped by cDNA/EST and Trace sequences. Sequence alignments between orthologous sites are also available.

Reference: Lee, J.Y., Yeh, I., Park, J.Y., and Tian, B. (2007). PolyA_DB 2: mRNA polyadenylation sites in vertebrate genes. Nucleic Acids Res. 35:D165-8.


PolyA site prediction and analysis tools

PolyA_SVM

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PolyA_SVM predicts polyA sites using 15 cis elements identified for human polyA sites.

Reference: Cheng, Y., Miura, R.M., and Tian, B. (2006). Prediction of mRNA polyadenylation sites by support vector machine. Bioinformatics 22:2320-5.

 
Please contact Bin Tian for questions/comments/suggestions.